Research Progress of Photothermal Nanomaterials and Bioreaction Degradation Mechanism in Cancer Therapy

Abstract

Abstract: Photothermal therapy (PTT) is an alternative new cancer treatment after surgery, radiotherapy and chemotherapy. Thinking about the characteristics of tumor photothermal therapy, the key factors of photothermal nanomaterials in clinical applications include theire photothermal conversion efficiency, surface modification activity, biocompatibility, biodegradability and low toxicity. With the development of photothermal nanomaterials, PTT holds immense potential in clinical translation. Up to now, four generation of photothermal nanomaterials have been developed, including noble metal nanoparticles, carbon based nanomaterials, metal and non-metallic compound nanomaterials and organic dyes.