Dear Colleagues,

Cytokines are signaling molecules that play a crucial role in the immune system's response to infection, inflammation, and injury. In the context of subarachnoid hemorrhage (SAH), several cytokines have been shown to impact the development of secondary brain injury. Elevated levels of Interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) in the cerebrospinal fluid of SAH patients are thought to contribute to developing cerebral vasospasm, a common complication of SAH that can lead to ischemia and further brain damage. Other cytokines, such as interleukin-1 beta (IL-1β) and interleukin-8 (IL-8), have also been implicated in the development of secondary brain injury following SAH.

Understanding the role of cytokines in the development of secondary brain injury following SAH is an area of active research. Targeting cytokines may represent a promising avenue for developing new treatments to improve patient outcomes. Therefore, we welcome contributions that examine the mechanisms by which cytokines contribute to secondary brain injury after SAH and investigate the potential of targeting cytokines to improve patient outcomes. Our goal is to advance knowledge in this critical area of medical research, and we look forward to receiving your contributions.

Dr. FNU Ruchika

Section Editor